Oxidative Radical Transnitrilation of Arylboronic Acids with Trityl Isocyanide
Zhiyuan Xu, Xiaojuan Liang, Huan Li
Abstract
We report a radical transnitrilation of arylboronic acids with trityl isocyanide in the presence of manganese(III) acetate. Many functional groups can be tolerated in this transformation, and a special positive effect of benzoic acid in this reaction has been observed.
Topics & Concepts
ChemistryIsocyanideManganeseBenzoic acidOxidative phosphorylationMedicinal chemistryCombinatorial chemistryOrganic chemistryBiochemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods