Litcius/Paper detail

Integration of innate immune signalling by caspase-8 cleavage of N4BP1

Alexander D. Gitlin, Klaus Heger, Alexander F. Schubert, Rohit Reja, Donghong Yan, Victoria C. Pham, Eric Suto, Juan Zhang, Youngsu Kwon, Emily Freund, Jing‐Qiong Kang, Anna Pham, Roger Caothien, Natasha Bacarro, Trent Hinkle, Min Xu, Brent S. McKenzie, Benjamin Haley, Wyne P. Lee, Jennie R. Lill, Merone Roose‐Girma, Monika Dohse, Joshua D. Webster, Kim Newton, Vishva M. Dixit

2020Nature115 citationsDOI

Topics & Concepts

TRIFFADDCytokineTLR3Caspase 8TLR4Tumor necrosis factor alphaFas ligandTLR9BiologyCell biologyImmunologyInnate immune systemTLR2Toll-like receptorCancer researchCaspaseSignal transductionImmune systemApoptosisProgrammed cell deathBiochemistryGeneGene expressionDNA methylationInflammasome and immune disordersinterferon and immune responsesImmune Response and Inflammation