Intraperitoneal Administration of a Cisplatin-Loaded Nanogel through a Hybrid System Containing an Alginic Acid-Based Nanogel and an <i>In Situ</i> Cross-Linkable Hydrogel for Peritoneal Dissemination of Ovarian Cancer
Kohei Yamaguchi, Osamu Hiraike, Haruna Iwaki, Kazuki Matsumiya, Noriko Nakamura, Kenbun Sone, Seiichi Ohta, Yutaka Osuga, Taichi Ito
Abstract
. This therapy may be considered a novel strategy for the treatment of advanced-stage ovarian cancer with KRAS mutations.
Topics & Concepts
NanogelOvarian cancerCisplatinIn vivoCancer researchKRASPharmacologyCancerChemotherapyMedicineBiologyMaterials scienceDrug deliveryInternal medicineNanotechnologyBiotechnologyColorectal cancerOvarian cancer diagnosis and treatmentIntraperitoneal and Appendiceal MalignanciesEndometriosis Research and Treatment