Enhanced photothermal heating and combination therapy of NIR dye <i>via</i> conversion to self-assembled ionic nanomaterials
Samantha Macchi, Amanda Jalihal, Nasrin Hooshmand, Mohd Muzammil Zubair, Samir V. Jenkins, Nabeel Alwan, Mostafa A. El‐Sayed, Nawab Ali, Robert J. Griffin, Noureen Siraj
Abstract
as compared to either the chemotherapeutic or photothermal parent compounds individually, due to a synergistic effect of the combined therapies, improved photophysical properties and their nanoparticles' morphology that enhanced the cellular uptake of the drugs. This study presents a general framework for the development of carrier-free dual-mechanism nanotherapeutics.
Topics & Concepts
Photothermal therapyNanomaterialsIonic bondingMaterials scienceNanotechnologyQuantum yieldNanoparticleFluorescenceChemistryOrganic chemistryPhysicsIonQuantum mechanicsNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisLuminescence and Fluorescent Materials