Litcius/Paper detail

Injured adult neurons regress to an embryonic transcriptional growth state

Gunnar Poplawski, Riki Kawaguchi, Erna van Niekerk, Paul Lu, Neil Mehta, Philip Canete, Richard Lie, Ioannis Dragatsis, Jessica M. Meves, Binhai Zheng, Giovanni Coppola, Mark H. Tuszynski

2020Nature252 citationsDOI

Topics & Concepts

TranscriptomeCorticospinal tractEmbryonic stem cellBiologySpinal cord injurySpinal cordRegeneration (biology)NeuroscienceNeural stem cellForelimbCell biologyStem cellGeneMedicineGene expressionGeneticsRadiologyMagnetic resonance imagingDiffusion MRINerve injury and regenerationMuscle Physiology and DisordersNeurogenesis and neuroplasticity mechanisms