Peptide ligands targeting FGF receptors promote recovery from dorsal root crush injury via AKT/mTOR signaling
Ying Zhao, Qiang Wang, Chen Xie, Yuling Cai, Xue Chen, Yuhui Hou, He Liu, Jianping Li, Min Yao, Shuangxi Chen, Wutian Wu, Xiaojia Chen, An Hong
Abstract
Our study revealed the significant therapeutic effect of CH02 on strengthening nerve regeneration and suggested a strategy for treating peripheral and central nervous system injuries.
Topics & Concepts
Fibroblast growth factor receptorCell biologyReceptor tyrosine kinaseFibroblast growth factorPeptideReceptorChemistryBiochemistryBiologySignal transductionFibroblast Growth Factor ResearchNerve injury and regenerationAxon Guidance and Neuronal Signaling