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Catalytic asymmetric inverse-electron-demand aza-Diels–Alder reaction of 1,3-diazadienes with 3-vinylindoles

Yu‐Hang Miao, Yuan‐Zhao Hua, Hao‐Jie Gao, Nan-Nan Mo, Min‐Can Wang, Guang‐Jian Mei

2022Chemical Communications20 citationsDOI

Abstract

A facile chiral phosphoric-acid catalyzed asymmetric inverse-electron-demand aza-Diels–Alder reaction of 1,3-diazadienes with 3-vinylindoles was established.

Topics & Concepts

StereocenterPhosphoric acidCatalysisChemistryYield (engineering)InverseDiels–Alder reactionDual (grammatical number)Combinatorial chemistryMedicinal chemistryOrganic chemistryEnantioselective synthesisMaterials scienceMathematicsGeometryMetallurgyArtLiteratureAsymmetric Synthesis and CatalysisSynthesis and Catalytic ReactionsOxidative Organic Chemistry Reactions
Catalytic asymmetric inverse-electron-demand aza-Diels–Alder reaction of 1,3-diazadienes with 3-vinylindoles | Litcius