New thiophene, thienopyridine and thiazoline-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents and multitargeting kinase inhibitors
Zahra M. Al-Amshany, Nada Y. Tashkandi, Ismail M. M. Othman, Manal M. Anwar, Eman S. Nossier
Topics & Concepts
ChemistryApoptosisThiopheneDocking (animal)Cell growthCell cycle checkpointKinasePharmacologyIC50PotencyCell cultureIn vitroCancer researchBiochemistryStereochemistryCell cycleBiologyMedicineNursingOrganic chemistryGeneticsCancer Mechanisms and TherapySynthesis and biological activityEnzyme function and inhibition