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Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient

Andrea Montesel, Claudio Bucolo, Victoria Mouvet, Emmanuelle Moret, Chiara M. Eandi

2020Frontiers in Pharmacology92 citationsDOIOpen Access PDF

Abstract

We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system.

Topics & Concepts

Central retinal artery occlusionMedicineCoronavirus disease 2019 (COVID-19)Central retinal arteryRetinalDiseaseOcclusionEndothelial dysfunctionPathogenesisRetinal Artery OcclusionVascular occlusionCardiologyOphthalmologyIntensive care medicineInternal medicineInfectious disease (medical specialty)Retinal and Optic ConditionsLong-Term Effects of COVID-19Ocular Diseases and Behçet’s Syndrome
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