The Who, What, When, and Where of Inpatient Direct Oral Penicillin Challenge—Implications for Health Services Implementation
Jason A. Trubiano, Sara Vogrin, Elise Mitri, Rebecca A. Hall, Ana Maria Copaescu, Jamie Waldron, Joseph De Luca, Morgan J. Rose, Geoff Mackay, Belinda Lambros, Abby Douglas, Natasha E. Holmes, Kyra Chua
Abstract
Inpatient direct oral challenge programs are increasingly deployed as part of antimicrobial stewardship initiatives to reduce the burden and impacts of penicillin allergy labels on antibiotic prescribing. Using data from a prospective, multicenter cohort inpatient penicillin allergy program, we identify the key targets for delabeling to aid health service implementation.
Topics & Concepts
PenicillinPenicillin allergyAntimicrobial stewardshipMedicineStewardship (theology)Antibiotic StewardshipIntensive care medicineAntibioticsEnvironmental healthAntibiotic resistancePolitical scienceBiologyMicrobiologyPoliticsLawDrug-Induced Adverse ReactionsPharmacovigilance and Adverse Drug ReactionsAntibiotic Use and Resistance