Simultaneous measurements of single gamma ray of 131I and annihilation radiation of 18F with Compton PET hybrid camera
Kenichiro Ogane, Mizuki Uenomachi, Kenji Shimazoe, M. Takahashi, Hiroyuki Takahashi, Yasuyuki Seto, Toshimitsu Momose
Abstract
In internal 131I therapy for thyroid cancer, a decision to continue treatment is made by comparing 131I scintigraphy and [18F]FDG-PET. However, with current SPECT and PET systems, simultaneous imaging of diagnostic PET nuclides and therapeutic 131I nuclides has not been achieved so far. Therefore, we demonstrated that the recently developed Compton PET hybrid camera with Ce:Gd3(Al,Ga)5O12 (GAGG)- Silicon Photomultiplier(SiPM) scintillation detectors can be used to simultaneously image 131I Compton image and 18F PET image.
Topics & Concepts
Silicon photomultiplierNuclideGamma cameraScintillationNuclear medicinePhysicsCompton scatteringOpticsGamma rayDetectorRadiochemistryMaterials scienceScintillatorNuclear physicsMedicineChemistryPhotonMedical Imaging Techniques and ApplicationsThyroid Cancer Diagnosis and TreatmentRadiation Therapy and Dosimetry