Advances in topiramate as prophylactic treatment for migraine
Chuan Hu, Yixin Zhang, Ge Tan
Abstract
It is well-known that topiramate as a kind of antiepileptic drug has been proved effective for migraine prevention in North America and Europe. However, topiramate is still viewed as an off-label medication for migraine treatment in China, partly because of the limited evidence in Chinese patients. We summarize the effects of topiramate on the frequency, severity, quality-of-life, and adverse event among migraine patients, including children and adolescent in this review, so as to provide reference for Chinese doctors.
Topics & Concepts
TopiramateMigraineMedicineAdverse effectProphylactic treatmentAntiepileptic drugEpilepsyQuality of life (healthcare)PediatricsPsychiatryIntensive care medicinePharmacologyInternal medicineNursingMigraine and Headache StudiesTrigeminal Neuralgia and TreatmentsRestless Legs Syndrome Research