The Spread of Insertion Sequences Element and Transposons in Carbapenem Resistant <i>Acinetobacter baumannii</i> in a Hospital Setting in Southwestern Iran
Zahra Hashemizadeh, Gholamreza Hatam, Javad Fathi, Fatemeh Aminazadeh, Hossein Hosseini-Nave, Mahtab Hadadi, Nafiseh Hosseinzadeh Shakib, Sodeh Kholdi, Abdollah Bazargani
Abstract
BACKGROUND: bacteria collected from patients in Shiraz, Iran. MATERIALS AND METHODS: isolates were obtained from different clinical specimens in two hospitals. The minimum inhibitory concentrations (MIC) of imipenem were determined and the prevalence of OXA Carbapenemases, Metallo-β-lactamases genes, insertion sequences (IS) elements, and transposons were evaluated by the polymerase chain reaction (PCR) method. Finally, molecular typing of the isolates was performed by the Enterobacterial Repetitive Intergenic Consensus-PCR method. RESULTS: , respectively. Considering an 80.0% cut off, clusters and four singletons were detected. CONCLUSION: bacteria as a public health concern.