Exosome-based rare earth nanoparticles for targeted<i>in situ</i>and metastatic tumor imaging with chemo-assisted immunotherapy
Bi Lin, Yanxing Wang, Kun Zhao, Wei‐Dong Lü, Xin Hui, Yaqun Ma, Ruichan Lv
Abstract
NIR II imaging and metastases of this platform can be proved. The chemotherapy, starvation therapy, and immunotherapy (immune checkpoint inhibitors of an anti-PD-L1 antibody) could achieve effective synergistic therapy for lung adenocarcinoma, and the immunotherapy can be further proved by the clinical data. This will provide a new strategy for the precise targeting and treatment of tumors.
Topics & Concepts
ImmunotherapyIn situExosomeRare earthMicrovesiclesChemistryCancer researchNanotechnologyMedicineMaterials scienceImmune systemImmunologyMineralogyBiochemistrymicroRNAOrganic chemistryGeneNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryExtracellular vesicles in disease