The major subunit of widespread competence pili exhibits a novel and conserved type IV pilin fold
Devon Sheppard, Jamie-Lee Berry, Rémi Denise, Eduardo P. C. Rocha, Stephen Matthews, Vladimir Pelicic
Abstract
exhibit a novel type IV pilin fold that is purely helical. Results from homology modeling analyses suggest that the unusual structure of ComGC is compatible with helical filament assembly. Because ComGC displays such a widespread distribution, these results have implications for hundreds of monoderm species.
Topics & Concepts
PilinPilusBiologyHorizontal gene transferFimbriae ProteinsGeneticsStreptococcus gordoniiProtein subunitPhylogenetic treeMicrobiologyGeneBacteriaEscherichia coliStreptococcusBacterial Genetics and BiotechnologyRNA and protein synthesis mechanismsGenomics and Phylogenetic Studies