A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers
Muhammad Babar Khawar, Ali Afzal, Muhammad Mujahid Ali, Haibo Sun
Abstract
Abstract The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting DNA methylation, introducing a novel approach to enhance early diagnostic precision.
Topics & Concepts
Molecularly imprinted polymerDNA methylationMaterials scienceEpigeneticsPolymerNanotechnologyDNAMethylationMolecular imprintingCombinatorial chemistryComputational biologyBiologyGeneticsGeneBiochemistryChemistrySelectivityGene expressionCatalysisComposite materialEpigenetics and DNA MethylationGenetic Syndromes and Imprinting