Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure
Cody D. Smith, Cameron A. Schmidt, Chien‐Te Lin, Kelsey H. Fisher‐Wellman, P. Darrell Neufer
Abstract
production and, in turn, the rate at which energy is expended via NNT-mediated proton conductance. This variable flux through redox circuits provides a potential compensatory mechanism for fine-tuning energy expenditure to energy balance in real time.
Topics & Concepts
RedoxBiophysicsElectron transport chainMitochondrionChemistryNAD+ kinaseFlux (metallurgy)NicotinamideBioenergeticsBiochemistryBiologyEnzymeInorganic chemistryOrganic chemistryMitochondrial Function and PathologyATP Synthase and ATPases ResearchAdipose Tissue and Metabolism