Anti-osteoporosis effects and regulatory mechanism of <i>Lindera aggregata</i> based on network pharmacology and experimental validation
Furong Wang, Peng‐Ze Rong, Juan Wang, Yu Xiao, Na Wang, Shengyu Wang, Zikai Xue, Junnan Chen, Wenlong Meng, Xin Peng
Abstract
. Our results demonstrated the reliability of the network pharmacology method, and also revealed the anti-OP effect and potential mechanism of RLA.
Topics & Concepts
PharmacologyCathepsin KRANKLBone resorptionOsteoclastPrednisoneMedicineChemistryInternal medicineReceptorActivator (genetics)Bone Metabolism and DiseasesBone health and osteoporosis researchBirth, Development, and Health