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Single-sequence protein structure prediction using a language model and deep learning

Ratul Chowdhury, Nazim Bouatta, Surojit Biswas, Christina Floristean, Anant Kharkar, Koushik Roy, Charlotte Rochereau, Gustaf Ahdritz, Joanna Zhang, George M. Church, Peter K. Sorger, Mohammed AlQuraishi

2022Nature Biotechnology425 citationsDOIOpen Access PDF

Topics & Concepts

Protein structure predictionComputer scienceArtificial intelligenceProtein structureProtein foldingSequence (biology)CASPDeep learningFolding (DSP implementation)Differentiable functionComputational biologyMachine learningBiologyMathematicsGeneticsEngineeringBiochemistryElectrical engineeringMathematical analysisProtein Structure and DynamicsMachine Learning in BioinformaticsRNA and protein synthesis mechanisms
Single-sequence protein structure prediction using a language model and deep learning | Litcius