Nanobubbles containing PD-L1 Ab and miR-424 mediated PD-L1 blockade, and its expression inhibition to enable and potentiate hepatocellular carcinoma immunotherapy in mice
Yun Liu, Qian Xie, Yao Ma, Chen Lin, Jinlin Li, Bing Hu, Chaoqi Liu, Yun Zhao
Topics & Concepts
ImmunotherapyPD-L1Cancer researchFlow cytometryAntibodyImmune systemAntigenTransfectionMolecular biologyHepatocellular carcinomaChemistryBiologyImmunologyGeneBiochemistryNanoplatforms for cancer theranosticsExtracellular vesicles in diseaseCancer Immunotherapy and Biomarkers