Citrate-based mussel-inspired magnesium whitlockite composite adhesives augmented bone-to-tendon healing
Xiaowei Yuan, Yitao Zhao, Jintao Li, Xuncai Chen, Zhihui Lu, Lianyong Li, Jinshan Guo
Abstract
Citrate-based mussel-inspired whitlockite composite adhesives (CMWAs) were developed and administered to the bone-tendon interface in anterior cruciate ligament (ACL) reconstruction. CMWAs could improve the initial bone-tendon bonding strength, promote the bony inward growth from the bone tunnel and enhance the chondrogenesis and osteogenesis of the bone-tendon interface, thus augmenting bone-to-tendon healing.
Topics & Concepts
WhitlockiteComposite numberAdhesiveMaterials scienceMusselMagnesiumBiomedical engineeringDentistryComposite materialMetallurgyCalciumMedicineBiologyEcologyLayer (electronics)Surgical Sutures and AdhesivesBone Tissue Engineering MaterialsHemostasis and retained surgical items