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Overexpression of the sulfate transporter‐encoding <i>SULTR2</i> increases chromium accumulation in <i>Chlamydomonas reinhardtii</i>

Yuxin Tang, Baolong Zhang, Zhaoyang Li, Ping Deng, Xuan Deng, Huan Long, Xun Wang, Kaiyao Huang

2023Biotechnology and Bioengineering16 citationsDOI

Abstract

Abstract Hexavalent chromium [Cr(Ⅵ)] is a highly toxic contaminant in aquatic systems, and microalgae represent promising bioremediators of metal‐containing wastewater. However, the metal‐binding capacity of algal cells is limited. Therefore, we improved the cellular Cr(Ⅵ) biosorption capacity of Chlamydomonas reinhardtii by overexpressing the sulfate transporter gene SULTR2 . SULTR2 was predominantly located in the cytoplasm of the cell, and few proteins mobilized to the cell membrane as a Cr transporter under Cr stress conditions. Intracellular Cr accumulation was almost doubled in SULTR2 ‐overexpressing transgenic strains after exposure to 30 μM K 2 Cr 2 O 7 for 4 d. Alginate‐based immobilization increased the rate of Cr removal from 43.81% to 88.15% for SULTR2 ‐overexpressing transgenic strains after exposure to 10 μM K 2 Cr 2 O 7 for 6 d. The immobilized cells also displayed a significant increase in nutrient removal efficiency compared to that of free‐swimming cells. Therefore, SULTR2 overexpression in algae has a great potential for the bioremediation of Cr(Ⅵ)‐containing wastewater.

Topics & Concepts

Chlamydomonas reinhardtiiTransporterChromiumSulfateChemistryBiochemistryGeneCell biologyBiophysicsBiologyOrganic chemistryMutantMercury impact and mitigation studiesEnvironmental Toxicology and EcotoxicologyAquaculture Nutrition and Growth
Overexpression of the sulfate transporter‐encoding <i>SULTR2</i> increases chromium accumulation in <i>Chlamydomonas reinhardtii</i> | Litcius