Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation
T. Hidaka, Kaori Hashiya, Toshikazu Bando, Ganesh N. Pandian, Hiroshi Sugiyama
Topics & Concepts
Mitochondrial DNAPoint mutationDNAHeLaMitochondrionBiologyMutantMutationBiochemistryMolecular biologyAlkylationChemistryIn vitroGeneCatalysisMitochondrial Function and PathologyATP Synthase and ATPases ResearchMetabolism and Genetic Disorders