Harnessing the tumor microenvironment to boost adoptive T cell therapy with engineered lymphocytes for solid tumors
Martina Spiga, Elisa Martini, Maria Chiara Maffia, Fabio Ciceri, Eliana Ruggiero, Alessia Potenza, Chiara Bonini
Topics & Concepts
Tumor microenvironmentChimeric antigen receptorCancer researchT cellT-cell receptorHoming (biology)ImmunologyAdoptive cell transferCell therapyStromaExtravasationCytotoxic T cellBiologyMedicineImmune systemCell biologyStem cellTumor cellsIn vitroImmunohistochemistryBiochemistryEcologyCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses