Stem cell biology needs a theory
Ben D. MacArthur
Abstract
Stem cell biologists are increasingly making use of computational models to decipher their data. However, there is sometimes uncertainty about what makes a "good" model. The purpose of this commentary is to argue for closer integration of experiment and theory in stem cell research and propose guidelines for good theory.
Topics & Concepts
BiologyStem cellComputational biologyCell biologyPluripotent Stem Cells ResearchSingle-cell and spatial transcriptomicsCancer Cells and Metastasis