Targeting Parasympathetic Activity to Improve Autonomic Tone and Clinical Outcomes
Matthew W. Kay, Vivek Jain, Gurusher Panjrath, David Mendelowitz
Abstract
In this review we will briefly summarize the evidence that autonomic imbalance, more specifically reduced parasympathetic activity to the heart, generates and/or maintains many cardiorespiratory diseases and will discuss mechanisms and sites, from myocytes to the brain, that are potential translational targets for restoring parasympathetic activity and improving cardiorespiratory health.
Topics & Concepts
Cardiorespiratory fitnessVagal toneNeuroscienceMedicineAutonomic nervous systemParasympathetic nervous systemMuscle tonePsychologyHeart rateInternal medicineBlood pressureHeart Rate Variability and Autonomic ControlNeuroscience of respiration and sleepCardiovascular Syncope and Autonomic Disorders