Discovery of the GSH responsive “Y-PROTACs” targeting ALK and CDK4/6 as a potential treatment for cancer
Shirui Wang, Dan Luo, Chunlan Pu, Xinyu Ma, Hongjia Zhang, Zhanzhan Feng, Rui Deng, Su Yu, Yuanyuan Liu, Qing Huang, Rui Li
Topics & Concepts
ChemistryIn vitroIC50Cancer researchCancerBiochemistryBiologyGeneticsProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisHistone Deacetylase Inhibitors Research