The bioavailability enhancement and insight into the action mechanism of poorly soluble natural compounds from co-crystals preparation: Oridonin as an example
Xin‐Ming Jia, Han Hao, Qian Zhang, Mengxin Yang, Nan Wang, Shilin Sun, Zenan Yang, Yiran Jin, Jing Wang, Yingfeng Du, Yingfeng Du
Topics & Concepts
BioavailabilityCytotoxicityPharmacologyChemistryCocrystalIC50NicotinamideMechanism of actionDownregulation and upregulationBiochemistryBiologyIn vitroOrganic chemistryGeneEnzymeMoleculeHydrogen bondBioactive Natural Diterpenoids ResearchMarine Sponges and Natural ProductsMicrobial Natural Products and Biosynthesis