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The gut microbiome molecular complex in human health and disease

Paul Wilmes, Camille Martin‐Gallausiaux, Marek Ostaszewski, Velma T. E. Aho, Polina V. Novikova, Cédric C. Laczny, Jochen G. Schneider

2022Cell Host & Microbe39 citationsDOIOpen Access PDF

Abstract

The human gut microbiome produces a functional complex of biomolecules, including nucleic acids, (poly)peptides, structural molecules, and metabolites. This impacts human physiology in multiple ways, especially by triggering inflammatory pathways in disease. At present, much remains to be learned about the identity of key effectors and their causal roles.

Topics & Concepts

BiologyMicrobiomeHuman microbiomeEffectorComputational biologyGut microbiomeNucleic acidDiseaseHuman diseaseHuman healthBioinformaticsCell biologyBiochemistryGeneMedicinePathologyEnvironmental healthGut microbiota and healthDiet and metabolism studiesNutritional Studies and Diet
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