Evaluation of the cytotoxicity and genotoxicity potential of synthetic diacetyl food flavoring in silico, in vivo, and in vitro
Mohamed Salama, Dina Mostafa Mohammed, Khaled Fahmy, Neima K. Al-Senosy, Naglaa Ebeed, Amr Farouk
Topics & Concepts
DiacetylDownregulation and upregulationGenotoxicityApoptosisIn vivoChemistryPharmacologyMolecular biologyTumor necrosis factor alphaCytotoxicityBiochemistryBiologyIn vitroToxicityImmunologyGeneBiotechnologyOrganic chemistryCarcinogens and Genotoxicity AssessmentGenomics, phytochemicals, and oxidative stressDrug-Induced Hepatotoxicity and Protection