Evaluating troponin elevation in patients with chronic kidney disease and suspected acute coronary syndrome
Lorenzo Braghieri, Osamah Badwan, Warren Skoza, Maan Fares, Venu Menon
Abstract
Many patients with chronic kidney disease have chronically elevated cardiac troponin levels, and if they present with symptoms suggesting an acute coronary syndrome, it is often difficult to determine if this is the correct diagnosis. This article briefly reviews the major challenges in diagnosing acute coronary syndrome in patients with chronic kidney disease, describes the mechanisms and prognostic significance of troponin elevation in chronic kidney disease, and provides a diagnostic algorithm to risk-stratify patients with chronic kidney disease who have troponin elevation and suspected acute coronary syndrome.
Topics & Concepts
MedicineKidney diseaseAcute coronary syndromeTroponinInternal medicineCardiologyDiseaseTroponin TST elevationIntensive care medicineMyocardial infarctionAcute Myocardial Infarction ResearchCardiac Imaging and DiagnosticsCoronary Interventions and Diagnostics