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Identification and structure–activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus

Qing Li, Xiaoyan Deng, Neng Jiang, Liuwei Meng, Junhao Xing, Weizhe Jiang, Yan‐Jun Xu

2021European Journal of Medicinal Chemistry20 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryPotencyIn vivoBioavailabilityBenzoic acidPharmacokineticsPharmacologyStereochemistryBiochemistryIn vitroBiotechnologyBiologyMedicineDiabetes Treatment and ManagementPeptidase Inhibition and AnalysisNeuropeptides and Animal Physiology
Identification and structure–activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus | Litcius