The anti-fatigue effect of the<i>Auxis thazard</i>oligopeptide<i>via</i>modulation of the AMPK/PGC-1α pathway in mice
Yushan Qu, Hongwu Ji, Wenkui Song, Shuo Peng, Suhong Zhan, Liuyi Wei, Ming Chen, Di Zhang, Shucheng Liu
Abstract
The anti-fatigue effect of the ATO has been confirmed for the first time and its mechanism was revealed from the modulation of the oxidative stress and AMPK/PGC-1α pathway in mice.
Topics & Concepts
AMPKGlycogenMalondialdehydeOligopeptideChemistryOxidative stressInternal medicineEndocrinologyCurcuminPropionateMuscle fatigueBiochemistryProtein kinase APhosphorylationMedicinePeptidePsychiatryElectromyographyProtein Hydrolysis and Bioactive PeptidesMuscle metabolism and nutritionBiochemical effects in animals