RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice
Denuja Karunakaran, Adam W. Turner, Anne‐Claire Duchez, Sébastien Soubeyrand, Adil Rasheed, David Smyth, David P. Cook, Majid Nikpay, Joshua W. Kandiah, Calvin Pan, Michèle Geoffrion, Richard Lee, Ludovic Boytard, Hailey Wyatt, My-Anh Nguyen, Paulina Lau, Markku Laakso, Bhama Ramkhelawon, Marcus Alvarez, Kirsi H. Pietiläinen, Päivi Pajukanta, Barbara C. Vanderhyden, Peter Liu, Scott B. Berger, Peter J. Gough, John Bertin, Mary‐Ellen Harper, Aldons J. Lusis, Ruth McPherson, Katey J. Rayner
Topics & Concepts
Adipose tissueInflammationBiologyRIPK1Proinflammatory cytokineEndocrinologyInternal medicineCancer researchImmunologyNecroptosisMedicineProgrammed cell deathApoptosisGeneticsAdipokines, Inflammation, and Metabolic DiseasesImmune Cell Function and InteractionImmune cells in cancer