AKT3 deficiency in M2 macrophages impairs cutaneous wound healing by disrupting tissue remodeling
Song Gu, Hanhao Dai, Xilian Zhao, Chang Gui, Jianchao Gui
Abstract
mice had an impaired ability to promote wound healing. Thus, the downregulation of AKT3 in M2 macrophages prolonged tissue remodeling and delayed cutaneous wound healing.
Topics & Concepts
Tissue remodelingWound healingTissue repairMedicinePathologyCancer researchBiologyInflammationCell biologyImmunologyWound Healing and TreatmentsPressure Ulcer Prevention and ManagementTissue Engineering and Regenerative Medicine