Double strain-release enables formal C–O/C–F and C–N/C–F ring-opening metathesis
Yulei Zhu, Jie Jia, Xiangyu Song, Chunyu Gong, Ying Xia
Abstract
The first ring-opening C(sp 3 )–O/C(sp 3 )–F bond metathesis reaction between gem -difluorinated cyclopropanes and epoxides is reported. Azetidine is also a suitable substrate for C–N/C–F bond metathesis.
Topics & Concepts
MetathesisOlefin metathesisDouble bondSalt metathesis reactionAcyclic diene metathesisRing-closing metathesisStrain (injury)Ring-opening metathesis polymerisationChemistryCombinatorial chemistryStereochemistryOrganic chemistryBiologyPolymerizationPolymerAnatomySynthetic Organic Chemistry MethodsChemical Synthesis and AnalysisOrganometallic Complex Synthesis and Catalysis