Development of novel nitric oxide-releasing quinolinedione/furoxan hybrids as NQO1 inhibitors for intervention of drug-resistant hepatocellular cancer
Xiaoyan Zhang, Jinfeng Ding, Feng Li, Hongmei Wu, Zhongyuan Xu, Weizhi Tao, Yichen Wang, Yongqiu Zheng, Yong Ling, Peng Zhu
Topics & Concepts
FuroxanChemistryNitric oxideApoptosisCancer cellReactive oxygen speciesAutophagyPharmacologyCytotoxic T cellCancerBiochemistryCancer researchIn vitroBiologyGeneticsOrganic chemistryBioactive Compounds and Antitumor AgentsGenomics, phytochemicals, and oxidative stressSynthesis and Biological Evaluation