A [1<sub>5</sub>]paracyclophenone and its fluorenone-containing derivatives: syntheses and binding to nerve agent mimics <i>via</i> aryl-CH hydrogen bonding interactions
Peiren Liu, Hongliang Wang, Zeng Hong, Xin Hong, Feihe Huang
Abstract
A [1<sub>5</sub>]paracyclophenone and its fluorenone-containing derivatives were synthesized. The novel macrocyclic host <bold>I</bold> binds nerve agent mimics through the ‘non-traditional’ aryl-CH hydrogen bonding interactions.
Topics & Concepts
ChemistryFluorenoneHydrogen bondArylCombinatorial chemistryStereochemistryPolymer chemistryMoleculeOrganic chemistryPolymerFluoreneAlkylSynthesis and Biological EvaluationStructural and Chemical Analysis of Organic and Inorganic CompoundsSynthesis and Characterization of Heterocyclic Compounds