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Suppression of BACE1 and amyloidogenic/RAGE axis by sitagliptin ameliorates PTZ kindling-induced cognitive deficits in rats

Marwa M. Safar, Nancy N. Shahin, Ahmed F. Mohamed, Noha F. Abdelkader

2020Chemico-Biological Interactions20 citationsDOI

Topics & Concepts

KindlingHippocampal formationPentylenetetrazolMorris water navigation taskNeuroprotectionEndocrinologyInternal medicineHippocampusSitagliptinNeurotrophic factorsEpilepsyMedicineGlycogen synthasePharmacologyNeuroscienceChemistryPsychologyReceptorDiabetes mellitusInsulinType 2 diabetesAnticonvulsantDiabetes Treatment and ManagementEpilepsy research and treatmentAlzheimer's disease research and treatments
Suppression of BACE1 and amyloidogenic/RAGE axis by sitagliptin ameliorates PTZ kindling-induced cognitive deficits in rats | Litcius