COVID-19 in patients with juvenile idiopathic arthritis: frequency and severity
Oksana Boyarchuk, Lilya Predyk, Iryna Yuryk
Abstract
The aim of the study was to determine the frequency and the course of COVID-19 infection in children with juvenile idiopathic arthritis (JIA). The study involved 51 patients with JIA aged 2 to 18 years. Evidence of COVID-19 was found in 10 (19.6%) patients with JIA. COVID-19 infection occurred more often in patients with systemic arthritis (OR = 6.1667, 95% CI: 1.2053–31.5511, p = 0.0289). The course of COVID-19 infection in patients with JIA was generally similar to the course in the pediatric population, despite immunosuppressive therapy. In 3 out of 10 patients the infection caused an exacerbation of JIA, which required therapy escalation.
Topics & Concepts
JuvenileCoronavirus disease 2019 (COVID-19)Arthritis2019-20 coronavirus outbreakMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Internal medicineVirologyBiologyDiseaseOutbreakGeneticsInfectious disease (medical specialty)Autoimmune and Inflammatory Disorders ResearchRheumatoid Arthritis Research and TherapiesOrthopedic Infections and Treatments