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Elephantopinolide A-P, germacrane-type sesquiterpene lactones from Elephantopus scaber induce apoptosis, autophagy and G2/M phase arrest in hepatocellular carcinoma cells

Ming Bai, Jingjie Chen, Wei Xu, Shu-Hui Dong, Qingbo Liu, Bin Lin, Xiao‐Xiao Huang, Guo‐Dong Yao, Shao‐Jiang Song

2020European Journal of Medicinal Chemistry58 citationsDOI

Topics & Concepts

ChemistryAutophagySesquiterpeneApoptosisHepatocellular carcinomaProtein kinase BIC50Cell cycle checkpointSorafenibMTT assayStereochemistryIn vitroCancer researchBiochemistryCell cycleBiologySesquiterpenes and Asteraceae StudiesPlant biochemistry and biosynthesisBioactive Natural Diterpenoids Research
Elephantopinolide A-P, germacrane-type sesquiterpene lactones from Elephantopus scaber induce apoptosis, autophagy and G2/M phase arrest in hepatocellular carcinoma cells | Litcius