pH-Sensitive ε-polylysine/polyaspartic acid/zein nanofiber membranes for the targeted release of polyphenols
Yingying Ma, LI Xiu-xia, Luyun Cai, Jianrong Li
Abstract
release study of phlorotannin, kaempferol and tannic acid indicated that about 62.35%, 63.51% and 73.65% of polyphenol release occurred at pH 6.8 for 8 h. The result of cytotoxicity assay in human colon cancer cells (HT-29) showed good biocompatibility of the zein nanofiber membranes. The investigation suggested that polyphenols can be successfully entrapped in the ε-polylysine-polyaspartic acid-zein nanofiber membranes for targeted delivery.
Topics & Concepts
Polyaspartic acidMembranePolyphenolNanofiberFourier transform infrared spectroscopyChemistryBiocompatibilityTannic acidPolylysineElectrospinningNuclear chemistryControlled releaseChromatographyPolymer chemistryBiochemistryChemical engineeringMaterials scienceOrganic chemistryPolymerNanotechnologyAntioxidantRaw materialEngineeringElectrospun Nanofibers in Biomedical ApplicationsNanocomposite Films for Food PackagingAdvanced Cellulose Research Studies