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Using RNA-seq to Assess Off-Target Effects of Antisense Oligonucleotides in Human Cell Lines

Sven Michel, Ksenija Schirduan, Yimin Shen, Richard Klar, Jörg Tost, Frank Jaschinski

2020Molecular Diagnosis & Therapy26 citationsDOI

Topics & Concepts

OligonucleotideBiologyAntisense RNAGeneComputational biologyRNAAntisense therapyGene expressionGeneticsMolecular biologyLocked nucleic acidDNA and Nucleic Acid ChemistryRNA Interference and Gene DeliveryRNA and protein synthesis mechanisms