The induced membrane technique for bone defects: Basic science, clinical evidence, and technical tips
Graeme Hoit, Michaël Kain, Jeremy W. Sparkman, Brent L. Norris, Janet D. Conway, John T. Watson, Paul Tornetta, Aaron Nauth
Abstract
The clinical management of large bone defects continues to be a difficult clinical problem to manage for treating surgeons. The induced membrane technique is a commonly employed strategy to manage these complex injuries and achieve bone union. Basic science and clinical evidence continue to expand to address questions related to the biology of the membrane and how interventions may impact clinical outcomes. In this review, we discuss the basic science and clinical evidence for the induced membrane technique as well as provide indications for the procedure and technical tips for performing the induced membrane technique.