Strategies for improving the safety and RNAi efficacy of noncovalent peptide/siRNA nanocomplexes
Jun Wang, Guang Chen, Nan Liu, Xiaoxia Han, Feng Zhao, Lei Zhang, P Chen
Topics & Concepts
RNA interferenceSmall interfering RNAPeptideCell-penetrating peptideChemistryBiocompatible materialComputational biologyNanotechnologyCationic polymerizationBiophysicsRNABiochemistryBiologyMaterials scienceMedicineGeneBiomedical engineeringOrganic chemistryRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesMicroRNA in disease regulation