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Metallomimetic Chemistry of a Cationic, Geometrically Constrained Phosphine in the Catalytic Hydrodefluorination and Amination of Ar–F Bonds

Karina Chulsky, Irina Malahov, Deependra Bawari, Roman Dobrovetsky

2023Journal of the American Chemical Society71 citationsDOIOpen Access PDF

Abstract

High Resolution Image Download MS PowerPoint Slide The synthesis, isolation, and reactivity of a cationic, geometrically constrained σ 3 -P compound in the hexaphenyl-carbodiphosphoranyl-based pincer-type ligand ( 1 + ) are reported. 1 + reacts with electron-poor fluoroarenes via an oxidative addition-type reaction of the C–F bond to the P III -center, yielding new fluorophosphorane-type species (P V ). This reactivity of 1 + was used in the catalytic hydrodefluorination of Ar–F bonds with PhSiH 3, and in a catalytic C–N bond-forming cross-coupling reactions between fluoroarenes and aminosilanes. Importantly, 1 + in these catalytic reactions closely mimics the mode of action of the transition metal-based catalysts.

Topics & Concepts

ChemistryCationic polymerizationReactivity (psychology)AminationCatalysisPincer movementPhosphineOxidative additionLigand (biochemistry)Medicinal chemistryTransition metalPhotochemistryPolymer chemistryOrganic chemistryBiochemistryAlternative medicinePathologyReceptorMedicineOrganometallic Complex Synthesis and CatalysisOrganoboron and organosilicon chemistrySynthesis and characterization of novel inorganic/organometallic compounds
Metallomimetic Chemistry of a Cationic, Geometrically Constrained Phosphine in the Catalytic Hydrodefluorination and Amination of Ar–F Bonds | Litcius