Full-length protein classification via cysteine fingerprinting in solid-state nanopores
Neeraj Soni, Zohar Rosenstock, Navneet C. Verma, K. Siddharth, Noam Talor, Jingqian Liu, Barak Marom, Anatoly B. Kolomeisky, Aleksei Aksimentiev, A. MELLER
Topics & Concepts
NanoporeCysteineOligonucleotideChemistryBiophysicsChromosomal translocationMolecular biophysicsNanotechnologyTarget proteinGene isoformNanopore sequencingComputational biologyProtein–protein interactionRobustness (evolution)Covalent bondBiochemistryMolecular dynamicsPlasma protein bindingBioorthogonal chemistryNanobiotechnologyProtein foldingTransport proteinProtein engineeringProtein structureCytosolAtomic force microscopyThreading (protein sequence)UbiquitinNanopore and Nanochannel Transport StudiesIon-surface interactions and analysisAdvanced Electron Microscopy Techniques and Applications