Adsorption of lysozyme into a charged confining pore
Daniel L. Z. Caetano, Ralf Metzler, Andrey G. Cherstvy, Sidney J. de Carvalho
Abstract
The hen egg-white lysozyme adsorbs into a charged confining pore in two orientations depending on the pH. The p K a of the residues closer to the pore surface is significantly affected by the protein–pore electrostatic interactions.
Topics & Concepts
LysozymeIsoelectric pointAdsorptionChemistryDebye lengthProtein adsorptionSurface chargeElectrostaticsChemical physicsCharge densityCrystallographyChemical engineeringIonPhysical chemistryOrganic chemistryEnzymePhysicsBiochemistryQuantum mechanicsEngineeringPolymer Surface Interaction StudiesSurfactants and Colloidal SystemsSpectroscopy and Quantum Chemical Studies