Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
Ling‐Yan Su, Yang Tian, Qiang Zheng, Yu Cao, Mengyu Yao, Shuangping Wang, Wen Xu, Chuyu Xi, Andrea Clocchiatti, Guangjun Nie, Hejiang Zhou
Topics & Concepts
Transferrin receptorLysosomeEndocytosisCell biologyIn vivoChimera (genetics)VesicleBiologyChemistryTransferrinReceptorBiochemistryMembraneEnzymeBiotechnologyGeneProtein Degradation and InhibitorsCellular transport and secretionCAR-T cell therapy research