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Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

John Janetzko, Ryoji Kise, Benjamin Barsi‐Rhyne, Dirk H. Siepe, Franziska M. Heydenreich, Kouki Kawakami, Matthieu Masureel, Shoji Maeda, K. Christopher García, Mark von Zastrow, Asuka Inoue, Brian K. Kobilka

2022Cell120 citationsDOIOpen Access PDF

Topics & Concepts

G protein-coupled receptorArrestinEndosomeBiologyCell biologyAllosteric regulationPhosphorylationReceptorSignal transductionBiochemistryIntracellularReceptor Mechanisms and SignalingCellular transport and secretionPancreatic function and diabetes
Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics | Litcius